The Molecules of Life

Physical and Chemical Principles

Author: John Kuriyan,Boyana Konforti,David Wemmer

Publisher: Garland Science

ISBN: 9780815341888

Category: Science

Page: 1008

View: 7991

"Key to making future advances in the areas of biochemistry and molecular medicine is a new generation of molecular biologists and biochemists who are able to harness the tools and insights of physics and chemistry to exploit the emergence of genomic and systems-level information in biology.The basic ideas of energy, entropy, equilibrium thermodynamics, transport processes and reaction kinetics are closely related to exciting issues in contemporary biology, such as protein folding, chaperones and prion diseases, DNA polymerase and ribosome fidelity, DNA recognition, drug design, signal transduction, ion channel function, motor protein action and the versatility of enzyme mechanism. Providing this physical chemistry and biochemical foundation is The "Molecules of Life," a new undergraduate textbook for undergraduate students majoring in biology or pre-med. It deepens our understanding of how life functions by illuminating the physical principles underpinning biological phenomena"--Provided by publisher.
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The Molecules of Life: Physical and Chemical Principles

Author: John Kuriyan,Boyana Konforti,David Wemmer

Publisher: Garland Science

ISBN: 1135088926

Category: Science

Page: 1031

View: 6146

The Molecules of Life is a textbook with a new approach to physical chemistry for the life sciences. Written for undergraduates majoring in biology or health sciences, it integrates fundamental concepts in thermodynamics and kinetics with an introduction to biological mechanism at the level of molecular structure.
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Molecular Biology of the Cell

Author: Bruce Alberts

Publisher: Garland Science

ISBN: 1317563743

Category: Science

Page: 1464

View: 4836

As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.
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e-Study Guide for: The Molecules of Life: Physical and Chemical Principles by John Kuriyan, ISBN 9780815341888

Author: Cram101 Textbook Reviews

Publisher: Cram101 Textbook Reviews

ISBN: 1478445068

Category: Education

Page: 110

View: 7117

Never Highlight a Book Again! Just the FACTS101 study guides give the student the textbook outlines, highlights, practice quizzes and optional access to the full practice tests for their textbook.
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Physical Chemistry for the Life Sciences

Author: Peter Atkins,Julio de Paula

Publisher: Oxford University Press, USA

ISBN: 0199564280

Category: Science

Page: 590

View: 9132

Peter Atkins and Julio de Paula offer a fully integrated approach to the study of physical chemistry and biology.
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Principles of Physical Chemistry

Author: Hans Kuhn,Horst-Dieter Försterling,David H. Waldeck

Publisher: John Wiley & Sons

ISBN: 0470089644

Category: Science

Page: 1032

View: 4027

Principles of Physical Chemistry presents a novel approach to physical chemistry that emphasizes the use of a few fundamental principles to quantitatively describe the nature of molecules and their assemblies. It begins with atoms and molecules, using the electron-in-a-box model to illustrate the essential features of quantum mechanics and why atoms and molecules exist. Thermodynamics is not introduced in the classical manner, considering the first and second law as postulates, but approached by studying assemblies of molecules statistically. The authors proceed to molecular assemblies of increasing complexity, evolving from ideal gases to real gases and solutions, then to macromolecules and supramolecular machines, and ending with the search for the logical conditions and chemical requirements for physicochemical processes leading to life's origin, the emergence of matter that carries information. This text is ideal for both undergraduate and graduate courses in physical chemistry, providing a basis for understanding the nature of chemical processes in biology, chemistry, and engineering.
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Biomolecular Thermodynamics

From Theory to Application

Author: Douglas Barrick

Publisher: CRC Press

ISBN: 1439800200

Category: Medical

Page: 524

View: 6986

"an impressive text that addresses a glaring gap in the teaching of physical chemistry, being specifically focused on biologically-relevant systems along with a practical focus.... the ample problems and tutorials throughout are much appreciated." –Tobin R. Sosnick, Professor and Chair of Biochemistry and Molecular Biology, University of Chicago "Presents both the concepts and equations associated with statistical thermodynamics in a unique way that is at visual, intuitive, and rigorous. This approach will greatly benefit students at all levels." –Vijay S. Pande, Henry Dreyfus Professor of Chemistry, Stanford University "a masterful?tour de force.... Barrick's rigor and scholarship come through in every chapter." –Rohit V. Pappu, Edwin H. Murty Professor of Engineering, Washington University in St. Louis This book provides a comprehensive, contemporary introduction to developing a quantitative understanding of how biological macromolecules behave using classical and statistical thermodynamics. The author focuses on practical skills needed to apply the underlying equations in real life examples. The text develops mechanistic models, showing how they connect to thermodynamic observables, presenting simulations of thermodynamic behavior, and analyzing experimental data. The reader is presented with plenty of exercises and problems to facilitate hands-on learning through mathematical simulation. Douglas E. Barrick is a professor in the Department of Biophysics at Johns Hopkins University. He earned his Ph.D. in biochemistry from Stanford University, and a Ph.D. in biophysics and structural biology from the University of Oregon.
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Physical Biochemistry

Principles and Applications

Author: David Sheehan

Publisher: John Wiley & Sons

ISBN: 1118687485

Category: Science

Page: 328

View: 3960

"As will be seen, there is not much missing here. I thought that the sections were well balanced, with rarely too much or too little on a given topic...This is a text to be welcomed by both teachers and students." BIOCHEMISTRY & MOLECULAR BIOLOGY EDUCATION (on the first edition) The second edition of this successful textbook explains the basic principles behind the key techniques currently used in the modern biochemical laboratory and describes the pros and cons of each technique and compares one to another. It is non-mathematical, comprehensive and approachable for students who are not physical chemists. A major update of this comprehensive, accessible introduction to physical biochemistry. Includes two new chapters on proteomics and bioinformatics. Introduces experimental approaches with a minimum of mathematics and numerous practical examples. Provides a bibliography at the end of each chapter. Written by an author with many years teaching and research experience, this text is a must-have for students of biochemistry, biophysics, molecular and life sciences and food science.
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Biophysical Chemistry

Author: Alan Cooper

Publisher: Royal Society of Chemistry

ISBN: 1782625100

Category: Science

Page: N.A

View: 5899

Biophysical Chemistry covers the physical chemistry of biological macromolecules and the experimental techniques used to study them. Topics covered include: an introduction to biological molecules; spectroscopy, mass spectrometry and hydrodynamics of macromolecules; a ""bluffer's guide"" to molecular thermodynamics; biomolecular kinetics; chromatography and electrophoresis; and single-molecule methods. The easily digestible, pragmatic approach captures the reader with the fascinating challenges the subject poses for theoretical and experimental scientists. This book will be ideal for early undergraduates studying chemical or physical sciences and will act as a basis for more advanced study. Students in other areas of biological sciences will appreciate the less intimidating approach to physical chemistry as demonstrated here. Ideal for the needs of undergraduate chemistry students, Tutorial Chemistry Texts is a major series consisting of short, single topic or modular texts concentrating on the fundamental areas of chemistry taught in undergraduate science courses. Each book provides a concise account of the basic principles underlying a given subject, embodying an independent-learning philosophy and including worked examples.
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Protein Actions: Principles and Modeling

Author: Ivet Bahar,Robert L. Jernigan,Ken A. Dill

Publisher: Garland Science

ISBN: 1351815016

Category: Science

Page: 336

View: 3263

Protein Actions: Principles and Modeling is aimed at graduates, advanced undergraduates, and any professional who seeks an introduction to the biological, chemical, and physical properties of proteins. Broadly accessible to biophysicists and biochemists, it will be particularly useful to student and professional structural biologists and molecular biophysicists, bioinformaticians and computational biologists, biological chemists (particularly drug designers) and molecular bioengineers. The book begins by introducing the basic principles of protein structure and function. Some readers will be familiar with aspects of this, but the authors build up a more quantitative approach than their competitors. Emphasizing concepts and theory rather than experimental techniques, the book shows how proteins can be analyzed using the disciplines of elementary statistical mechanics, energetics, and kinetics. These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.
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Single Molecule Science

Physical Principles and Models

Author: Dmitrii E. Makarov

Publisher: CRC Press

ISBN: 1466559527

Category: Science

Page: 214

View: 4204

The observation and manipulation of individual molecules is one of the most exciting developments in modern molecular science. Single Molecule Science: Physical Principles and Models provides an introduction to the mathematical tools and physical theories needed to understand, explain, and model single-molecule observations. This book explains the physical principles underlying the major classes of single-molecule experiments such as fluorescence measurements, force-probe spectroscopy, and nanopore experiments. It provides the framework needed to understand single-molecule phenomena by introducing all the relevant mathematical and physical concepts, and then discussing various approaches to the problem of interpreting single-molecule data. The essential concepts used throughout this book are explained in the appendices and the text does not assume any background beyond undergraduate chemistry, physics, and calculus. Every effort has been made to keep the presentation self-contained and derive results starting from a limited set of fundamentals, such as several simple models of molecular dynamics and the laws of probability. The result is a book that develops essential concepts in a simple yet rigorous way and in a manner that is accessible to a broad audience.
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Physical Chemistry

Principles and Applications in Biological Sciences

Author: Ignacio Tinoco

Publisher: Pearson College Division


Category: Science

Page: 740

View: 3855

This best-selling volume presents the principles and applications of physical chemistry as they are used to solve problems in biology and medicine. The First Law; the Second Law; free energy and chemical equilibria; free energy and physical Equilibria; molecular motion and transport properties; kinetics: rates of chemical reactions; enzyme kinetics; the theory and spectroscopy of molecular structures and interactions: molecular distributions and statistical thermodynamics; and macromolecular structure and X-ray diffraction. For anyone interested in physical chemistry as it relates to problems in biology and medicine.
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Solutions Manual to Accompany Physical Chemistry for the Life Sciences

Author: C. A. Trapp,M. P. Cady

Publisher: N.A

ISBN: 0199600325

Category: Chemistry, Physical and theoretical

Page: 339

View: 8595

The Solutions Manual to accompany Physical Chemistry for the Life Sciences 2e contains fully-worked solutions to all end-of-chapter discussion questions and exercises featured in the book. The manual provides helpful comments and friendly advice to aid understanding. It is also a valuableresource for any lecturer who wishes to use the extensive selection of exercises featured in the text to support either formative or summative assessment, and wants labour-saving, ready access to the full solutions to these questions.
Posted in Chemistry, Physical and theoretical

Structure and Mechanism in Protein Science

A Guide to Enzyme Catalysis and Protein Folding

Author: Alan Fersht

Publisher: World Scientific

ISBN: 9813225181

Category: Science

Page: 652

View: 7613

This book is a guide for advanced undergraduates, post-graduates and researchers to the fundamental principles in studying kinetics and mechanism of processes concerning proteins. It provides a rare broad overview that concentrates on fundamental principles and understanding underlying the physics and chemistry. It is a single author text by someone who has direct experience in all of the areas covered.
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Modern Methods for Theoretical Physical Chemistry of Biopolymers

Author: Evgeni Starikov,James P. Lewis,Shigenori Tanaka

Publisher: Elsevier

ISBN: 9780080461014

Category: Science

Page: 604

View: 7653

Modern Methods for Theoretical Physical Chemistry of Biopolymers provides an interesting selection of contributions from an international team of researchers in theoretical chemistry. This book is extremely useful for tackling the complicated scientific problems connected with biopolymers' physics and chemistry. The applications of both the classical molecular-mechanical and molecular-dynamical methods and the quantum chemical methods needed for bridging the gap to structural and dynamical properties dependent on electron dynamics are explained. Also included are ways to deal with complex problems when all three approaches need to be considered at the same time. The book gives a rich spectrum of applications: from theoretical considerations of how ATP is produced and used as ‘energy currency’ in the living cell, to the effects of subtle solvent influence on properties of biopolymers and how structural changes in DNA during single-molecule manipulation may be interpreted. · Presents modern successes and trends in theoretical physical chemistry/chemical physics of biopolymers · Topics covered are of relevant importance to rapidly developing areas in science such as nanotechnology and molecular medicine · Quality selection of contributions from renowned scientists in the field
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Lehninger Principles of Biochemistry

Author: David L. Nelson,Albert L. Lehninger,Michael M. Cox

Publisher: Macmillan

ISBN: 071677108X

Category: Science

Page: 1158

View: 8849

Authors Dave Nelson and Mike Cox combine the best of the laboratory and best of the classroom, introducing exciting new developments while communicating basic principles of biochemistry.
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Physical Chemistry of Macromolecules

Basic Principles and Issues

Author: S. F. Sun

Publisher: John Wiley & Sons

ISBN: 9780471623564

Category: Technology & Engineering

Page: 549

View: 4399

Integrating coverage of polymers and biological macromolecules into a single text, Physical Chemistry of Macromolecules is carefully structured to provide a clear and consistent resource for beginners and professionals alike. The basic knowledge of both biophysical and physical polymer chemistry is covered, along with important terms, basic structural properties and relationships. This book includes end of chapter problems and references, and also: Enables users to improve basic knowledge of biophysical chemistry and physical polymer chemistry. Explores fully the principles of macromolecular chemistry, methods for determining molecular weight and configuration of molecules, the structure of macromolecules, and their separations.
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Principles and Problems in Physical Chemistry for Biochemists

Author: Nicholas C. Price

Publisher: Oxford University Press on Demand

ISBN: 9780198792819

Category: Science

Page: 401

View: 9500

What use is physical chemistry to the student of biochemistry and biology? This central question is answered in this book mainly through the use of worked examples and problems. The book starts by introducing the laws of thermodynamics, and then uses these laws to derive the equations relevant to the student in dealing with chemical equilibria (including the binding of small molecules to proteins), properties of solutions, acids and bases, and oxidation-reduction processes. The student is thus shown how a knowledge of thermodynamic qualities makes it possible to predict whether, and how, a reaction will proceed. Thermodynamics, however, gives no information about how fast a reaction will happen. The study of the rates at which processes occur (kinetics) forms the second main theme of the book. This section poses and answers questions such as `how is the rate of a reaction affected by temperature, pH, ionic strength, and the nature of the reactants? These same ideas are then shown to be useful in the study of enzyme-catalysed reactions.
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Molecules of Life

Author: Trace Jordan,Neville Kallenbach

Publisher: N.A

ISBN: 9780199946174


Page: 624

View: 2968

Chemistry: The Molecules of Life is the only textbook for non-majors that focuses on the fundamental chemistry of biological molecules and everyday life. It uses the chemistry of life to introduce, explain, and apply chemical principles. Each chapter begins with a framing question to stimulatestudents' interest. Many framing questions are pertinent to students' health, whereas others address foundational scientific topics. Scientific content in each chapter is introduced on a "need-to-know" basis that is related to the framing question. By the end of the chapter, students will be able toanswer the question using the chemical concepts they have learned.Chemistry: The Molecules of Life is designed for students who have a variety of academic and career interests, not all of which necessarily align with the sciences or health professions. Its authors believe that all undergraduate students - not just science majors - need to be educated aboutscientific knowledge and reasoning in order to make informed decisions about their personal well-being and important societal issues. Have you ever thought about how antibiotic medications work, or why it is important to take the entire dose that the doctor prescribed? Many of us also take a vitaminsupplement, often in the form of a daily multivitamin. Do you know what roles these vitamins play in our body, or why the recommended daily dose for some vitamins is much lower than for others? Does the federal government regulate vitamin supplements with the same scrutiny that it applies topharmaceuticals? Chemistry: The Molecules of Life examines relevant topics such as these and many more.Scientific knowledge is constantly advancing. Almost daily, the media reports on a new scientific discovery, a new interpretation of what foods or activities are good or bad for us, or the societal impact of a new medical breakthrough. Given this rapid progress, science cannot be presented as acollection of facts to be memorized. After a short time, even the most current scientific knowledge becomes outdated. Instead, students need to understand how scientists investigate the natural world-the methods they use, the evidence they generate, and the conclusions they make based on thatevidence. For this reason, each chapter of Chemistry: The Molecules of Life describes examples of scientific discovery. By analyzing these case studies, students will develop the critical thinking skills necessary to thoughtfully evaluate scientific information that is presented in the news media orobtained from other sources.
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