Significant advances in our knowledge of genetics were made during the twentieth century but in the most recent decades, genetic research has dramatically increased its impact throughout society. Genetic issues are now playing a large role in health and public policy, and new knowledge in this field will continue to have significant implications for individuals and society. Written for the non-majors human genetics course, Human Genetics, 3E will increase the genetics knowledge of students who are learning about human genetics for the first time. This thorough revision of the best-selling Human Genome,2E includes entirely new chapters on forensics, stem cell biology, bioinformatics, and societal/ethical issues associated with the field. New special features boxes make connections between human genetics and human health and disease. Carefully crafted pedagogy includes chapter-opening case studies that set the stage for each chapter; concept statements interspersed throughout the chapter that keep first-time students focused on key concepts; and end-of-chapter questions and critical thinking activities. This new edition will contribute to creating a genetically literate student population that understands basic biological research, understands elements of the personal and health implications of genetics, and participates effectively in public policy issues involving genetic information . Includes topical material on forensics, disease studies, and the human genome project to engage non-specialist students Full, 4-color illustration program enhances and reinforces key concepts and themes Uniform organization of chapters includes interest boxes that focus on human health and disease, chapter-opening case studies, and concept statements to engage non-specialist readers
Author: Julia E. Richards,R. Scott Hawley
Publisher: Academic Press
This simple, concise introduction to the HGP for the general reader explores the origins of the genome project and reactions in the scientific community; important technologies and techniques; institutions connected with the HGP, including designated genome centers, important suppliers of resources, and corporations; systems of communication; and ethical, legal, and social issues. A publication of the Biomolecular Sciences Initiative of CHF's Beckman Center for the History of Chemistry.
Technologies, People, and Institutions
Author: Susan L. Speaker,M. Susan Lindee,Elizabeth Hanson
Publisher: Chemical Heritage Foundation
"In my view, [Murphy] has written the most incisive general critical essay on the Human Genome Project yet to appear."--Troy Duster, Director, Institute for the Study of Social Change, University of California, Berkeley "In my view, [Murphy] has written the most incisive general critical essay on the Human Genome Project yet to appear."--Troy Duster, Director, Institute for the Study of Social Change, University of California, Berkeley
Author: Timothy F. Murphy,Marc Lappé
Publisher: Univ of California Press
Completion of the Human Genome Project is just the tip of the iceberg in our understanding of human genetics. How can information gathered during the Human Genome Project be used? This brief booklet explains in accessible language what readers need to understand about the Human Genome Project, including the background, findings, and social and ethical implications. The author, Michael Palladino, also includes relevant Web resources and exercises for readers.
Author: Michael Angelo Palladino
Publisher: Benjamin-Cummings Publishing Company
Leading medical genetics scholar Moyra Smith reviews current and recent work in genetics and genomics to assess progress in understanding human variation and the pathogenesis of common and rare diseases in which genetics plays a role. Smith provides an exceptional overview of the most important biomedical progress arising from the greatly increased genetic information base generated by gene mapping and the sequencing of the complete Human Genome. This book addresses into a wide spectrum of topics associated with human genetics and genomics, including: Human origins; migrations and human population diversity gained though genomic analyses. The complexities of psychiatric diseases that are influenced by genetics. The pathogenesis of late-onset neurological diseases such as Alzheimer’s, Parkinsonism, and ALS. Key aspects of protein misfolding. Gene-environment interactions in DNA damage and repair and DNA instability. Micro RNAs and mRNA translation. Epigenetics. New functions for old enzymes in cancer.
Insights into Human Variation and Disease Susceptibility
Author: Moyra Smith
Publisher: FT Press
Filled with stunning full-color illustrations, the editors of Nature present an authoritative guide to human genome sequencing, history's most significant discovery, that covers a vast array of information including genetics, basic biology, the key players, the project's landmark events, and its political, social, and scientific impact, and includes the full text of Nature's paper that divulged the human genome.
Author: Carina Dennis,Richard B. Gallagher
Publisher: Palgrave Macmillan
"The volume deserves our serious attention. The authors have provided us an invaluable primer about the HGP and its implications for the future of American health care." -- Jurimetrics "This book does make a real contribution... in explaining why the genetics revolution holds so much promise and why it is so difficult to bring that promise to fruition." -- The Journal of Legal Medicine "... marked by a forward-looking, analytically and empirically grounded thematic coherence. The editors' carefully crafted template and contributions successfully focus and organize the material." -- Annals of Internal Medicine "Excellent" -- Canadian Medical Association Journal "The editors have done a very good job integrating the contents into a very useful and readable information source." -- Choice "... this highly focused book is a well-written, thoughtful, and insightful consideration of the HGP and is valuable reading for anyone concerned with the future of our country's medical infrastructure." -- Science Books & Films (**Highly recommended) "A distinguished group of scientists, lawyers, and scholars have written a coherent, readable account of the legal, medical, ethical, and policy issues many (if not all) of us will be wrestling with on both a personal and a public level, as a result of current genetic research." -- Library Journal "Each of the contributors is a distinguished authority on the topic. Ethicists, especially, will find well-developed presentation of issues, with exposition of the differing ethical assumptions in tension in the society debate." -- Doody's Health Sciences Book Review Home Page How will the science of gene mapping and gene manipulation affect health care? Leading scholars explore the clinical, ethical, legal, and policy implications of the Human Genome Project for the forms of health care, who delivers it, who receives it, and who pays for it.
Author: Thomas H. Murray,Mark A. Rothstein,Robert F. Murray, Jr.
Publisher: Indiana University Press
Humanity's physical design flaws have long been apparent--we get hemorrhoids and impacted wisdom teeth, for instance--but do the imperfections extend down to the level of our genes? Inside the Human Genome is the first book to examine the philosophical question of why, from the perspectives of biochemistry and molecular genetics, flaws exist in the biological world. Distinguished evolutionary geneticist John Avise offers a panoramic yet penetrating exploration of the many gross deficiencies in human DNA--ranging from mutational defects to built-in design faults--while at the same time offering a comprehensive treatment of recent findings about the human genome. The author shows that the overwhelming scientific evidence for genomic imperfection provides a compelling counterargument to intelligent design. He also develops a case that theologians should welcome rather than disavow these discoveries. The evolutionary sciences can help mainstream religions escape the shackles of Intelligent Design, and thereby return religion to its rightful realm--not as the secular interpreter of the biological minutiae of our physical existence, but rather as a respectable philosophical counselor on grander matters of ultimate concern.
A Case for Non-Intelligent Design
Author: John C. Avise
Publisher: Oxford University Press
Describes potential uses for the ten-year, multimillion dollar Human Genome Project and its process of gene mapping; includes web citation for an interactive map of chromosomes.
Author: James Toriello
Publisher: The Rosen Publishing Group, Inc
A concise description of the structure of the human genome and the ways in which recent knowledge is influencing medical research and practice. If you have any interest in the Human Genome Project, this book is a must!
Author: T. Strachan
Publisher: Bios Scientific Pub Limited
Advances in genetic science and medicine raise questions for us all, such as: How far should we intervene in 'natural' processes? How far should we go to alleviate suffering? What constitutes a worthwhile life? Exploring these questions and more, this book considers theological, ethical and legal aspects relating to the human genome.
Theological, Legal and Scientific Perspectives
Author: Mark Bratton
Publisher: Church House Publishing
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Author: Committee on Mapping and Sequencing the Human Genome,Commission on Life Sciences,Division on Earth and Life Studies,National Research Council
Publisher: National Academies Press
Explores the ethical issues posed by genetic engineering.
The Human Genome Project and Theology
Author: Susan Brooks Thistlethwaite
Publisher: Fortress Press
The perfect resource for nursing students, as well as practicing nurses and physicians, this unique text explains the basics of the human genome: what it is, what it does, and its implications in health and disease.
Author: Edwin H. McConkey
Publisher: Jones & Bartlett Learning
Category: Health & Fitness
Describes the ten-year, multimillion dollar Human Genome Project and its process of gene mapping; includes concerns of critics of the project.
Cracking the Genetic Code of Life
Author: Thomas F. Lee
Begun formally in 1990, the U.S. Human Genome Project's (HGP) goals were to identify all the 20,000 to 25,000 genes in human DNA, determine the sequences of the three billion chemical base pairs that make up human DNA, store this information in databases, improve tools for data analysis, and transfer related technologies to the private sector. It was the first large scientific undertaking to address potential issues that arose from project data, and opened up vast possibilities for the use of genetic data and the alteration of our genetic makeup. This volume is the first to address the diverse range of ethical issues arising from the HGP, and enables professors to bring this critically important topic to life in the classroom. ';
Ethical Issues and Practical Strategies
Author: Aine Donovan,Ronald Michael Green
Drawing the Map of Life is the dramatic story of the Human Genome Project from its origins, through the race to order the 3 billion subunits of DNA, to the surprises emerging as scientists seek to exploit the molecule of heredity. It's the first account to deal in depth with the intellectual roots of the project, the motivations that drove it, and the hype that often masked genuine triumphs. Distinguished science journalist Victor McElheny offers vivid, insightful profiles of key people, such as David Botstein, Eric Lander, Francis Collins, James Watson, Michael Hunkapiller, and Craig Venter. McElheny also shows that the Human Genome Project is a striking example of how new techniques (such as restriction enzymes and sequencing methods) often arrive first, shaping the questions scientists then ask. Drawing on years of original interviews and reporting in the inner circles of biological science, Drawing the Map of Life is the definitive, up-to-date story of today's greatest scientific quest. No one who wishes to understand genome mapping and how it is transforming our lives can afford to miss this book.
Inside the Human Genome Project
Author: Victor K. McElheny
Examines the Human Genome Project and its impact on the understanding of human development, and explores the scientific, social, and ethical issues it raises
Scientific and Social Issues in the Human Genome Project
Author: Daniel J. Kevles,Leroy E. Hood
Publisher: Harvard University Press