Significant advances in our knowledge of genetics were made during the twentieth century but in the most recent decades, genetic research has dramatically increased its impact throughout society. Genetic issues are now playing a large role in health and public policy, and new knowledge in this field will continue to have significant implications for individuals and society. Written for the non-majors human genetics course, Human Genetics, 3E will increase the genetics knowledge of students who are learning about human genetics for the first time. This thorough revision of the best-selling Human Genome,2E includes entirely new chapters on forensics, stem cell biology, bioinformatics, and societal/ethical issues associated with the field. New special features boxes make connections between human genetics and human health and disease. Carefully crafted pedagogy includes chapter-opening case studies that set the stage for each chapter; concept statements interspersed throughout the chapter that keep first-time students focused on key concepts; and end-of-chapter questions and critical thinking activities. This new edition will contribute to creating a genetically literate student population that understands basic biological research, understands elements of the personal and health implications of genetics, and participates effectively in public policy issues involving genetic information . Includes topical material on forensics, disease studies, and the human genome project to engage non-specialist students Full, 4-color illustration program enhances and reinforces key concepts and themes Uniform organization of chapters includes interest boxes that focus on human health and disease, chapter-opening case studies, and concept statements to engage non-specialist readers
Author: Julia E. Richards,R. Scott Hawley
Publisher: Academic Press
Leading medical genetics scholar Moyra Smith reviews current and recent work in genetics and genomics to assess progress in understanding human variation and the pathogenesis of common and rare diseases in which genetics plays a role. Smith provides an exceptional overview of the most important biomedical progress arising from the greatly increased genetic information base generated by gene mapping and the sequencing of the complete Human Genome. This book addresses into a wide spectrum of topics associated with human genetics and genomics, including: Human origins; migrations and human population diversity gained though genomic analyses. The complexities of psychiatric diseases that are influenced by genetics. The pathogenesis of late-onset neurological diseases such as Alzheimer’s, Parkinsonism, and ALS. Key aspects of protein misfolding. Gene-environment interactions in DNA damage and repair and DNA instability. Micro RNAs and mRNA translation. Epigenetics. New functions for old enzymes in cancer.
Insights into Human Variation and Disease Susceptibility
Author: Moyra Smith
Publisher: FT Press
"In my view, [Murphy] has written the most incisive general critical essay on the Human Genome Project yet to appear."--Troy Duster, Director, Institute for the Study of Social Change, University of California, Berkeley "In my view, [Murphy] has written the most incisive general critical essay on the Human Genome Project yet to appear."--Troy Duster, Director, Institute for the Study of Social Change, University of California, Berkeley
Author: Timothy F. Murphy,Marc Lappé
Publisher: Univ of California Press
This simple, concise introduction to the HGP for the general reader explores the origins of the genome project and reactions in the scientific community; important technologies and techniques; institutions connected with the HGP, including designated genome centers, important suppliers of resources, and corporations; systems of communication; and ethical, legal, and social issues. A publication of the Biomolecular Sciences Initiative of CHF's Beckman Center for the History of Chemistry.
Technologies, People, and Institutions
Author: Susan L. Speaker,M. Susan Lindee,Elizabeth Hanson
Publisher: Chemical Heritage Foundation
Cracking the Genetic Code of Life
Author: Thomas F. Lee
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Author: Committee on Mapping and Sequencing the Human Genome,Commission on Life Sciences,Division on Earth and Life Studies,National Research Council
Publisher: National Academies Press
Filled with stunning full-color illustrations, the editors of Nature present an authoritative guide to human genome sequencing, history's most significant discovery, that covers a vast array of information including genetics, basic biology, the key players, the project's landmark events, and its political, social, and scientific impact, and includes the full text of Nature's paper that divulged the human genome.
Author: Carina Dennis,Richard B. Gallagher
Publisher: Palgrave Macmillan
Completion of the Human Genome Project is just the tip of the iceberg in our understanding of human genetics. How can information gathered during the Human Genome Project be used? This brief booklet explains in accessible language what readers need to understand about the Human Genome Project, including the background, findings, and social and ethical implications. The author, Michael Palladino, also includes relevant Web resources and exercises for readers.
Author: Michael Angelo Palladino
Publisher: Benjamin-Cummings Publishing Company
James Watson, a discoverer of the structure of DNA, described it as "the most golden of molecules," the true chemical for life. Indeed, it is the essential component from which our genes are made. In it is encoded the genetic language that controls our destinies. Astonishingly powerful, just six millionths of a gram of DNA carries as much information as ten volumes of the Oxford English Dictionary. The "Book of Man," is the term used by Walter Bodmer and Robin McKie for the DNA that is the instruction set according to which all humans are made. At conception, a single cell--the fertilized egg--is produced, and it is this one cell that has the potential to form a new and unique individual under the guidance of the DNA within its nucleus. The human body is made up of a hundred million million cells of many different sorts, and all contain the inherited information that comes from that first, single cell created at fertilization. Bodmer and McKie assert that when we learn how to read DNA's pages and chapters we will obtain the information relevant to the understanding of most diseases, individual differences in behavior, and a new awareness of our own history and evolution. The Book of Man explores how genetic information is now being read and interpreted by focusing on biology's most ambitious undertaking to date--the Human Genome Project, an attempt to uncover all the 100,000 genes that control our development and detail the DNA alphabet of each. The authors go on to wrestle with the moral and ethical issues of modern genetics, making a case for a rational appraisal of genetic engineering and for the public to become sufficiently "DNA literate" in order to appreciate the crucial role it plays in our lives. From Gregor Mendel's discovery of the laws of inheritance to the high-tech, crime-stopping power of forensics science and the fascinating but sometimes troublesome implications of the latest science of genetic engineering, The Book of Man brilliantly explores and explains the quest that is changing our understanding of what it means to be a human being.
The Human Genome Project and the Quest to Discover Our Genetic Heritage
Author: Walter Fred Bodmer,Robin McKie
Publisher: Oxford University Press on Demand
Representing a crucial scientific advance for humankind, the study of the human genome is of incalculable importance and something we should all understand. With this one book you will gain the insight necessary to recognize and appreciate the dramatic impact that genomic science is making, and will make, on the way we live.
The Book of Essential Knowledge
Author: John Quackenbush
Publisher: Imagine Publishing
Drawing the Map of Life is the dramatic story of the Human Genome Project from its origins, through the race to order the 3 billion subunits of DNA, to the surprises emerging as scientists seek to exploit the molecule of heredity. It’s the first account to deal in depth with the intellectual roots of the project, the motivations that drove it, and the hype that often masked genuine triumphs. Distinguished science journalist Victor McElheny offers vivid, insightful profiles of key people, such as David Botstein, Eric Lander, Francis Collins, James Watson, Michael Hunkapiller, and Craig Venter. McElheny also shows that the Human Genome Project is a striking example of how new techniques (such as restriction enzymes and sequencing methods) often arrive first, shaping the questions scientists then ask. Drawing on years of original interviews and reporting in the inner circles of biological science, Drawing the Map of Life is the definitive, up-to-date story of today’s greatest scientific quest. No one who wishes to understand genome mapping and how it is transforming our lives can afford to miss this book.
Inside the Human Genome Project
Author: Victor K. McElheny,K McElheny
Publisher: Basic Books
A concise description of the structure of the human genome and the ways in which recent knowledge is influencing medical research and practice. If you have any interest in the Human Genome Project, this book is a must!
Author: T. Strachan
Publisher: Bios Scientific Pub Limited
"The volume deserves our serious attention. The authors have provided us an invaluable primer about the HGP and its implications for the future of American health care." -- Jurimetrics "This book does make a real contribution... in explaining why the genetics revolution holds so much promise and why it is so difficult to bring that promise to fruition." -- The Journal of Legal Medicine "... marked by a forward-looking, analytically and empirically grounded thematic coherence. The editors' carefully crafted template and contributions successfully focus and organize the material." -- Annals of Internal Medicine "Excellent" -- Canadian Medical Association Journal "The editors have done a very good job integrating the contents into a very useful and readable information source." -- Choice "... this highly focused book is a well-written, thoughtful, and insightful consideration of the HGP and is valuable reading for anyone concerned with the future of our country's medical infrastructure." -- Science Books & Films (**Highly recommended) "A distinguished group of scientists, lawyers, and scholars have written a coherent, readable account of the legal, medical, ethical, and policy issues many (if not all) of us will be wrestling with on both a personal and a public level, as a result of current genetic research." -- Library Journal "Each of the contributors is a distinguished authority on the topic. Ethicists, especially, will find well-developed presentation of issues, with exposition of the differing ethical assumptions in tension in the society debate." -- Doody's Health Sciences Book Review Home Page How will the science of gene mapping and gene manipulation affect health care? Leading scholars explore the clinical, ethical, legal, and policy implications of the Human Genome Project for the forms of health care, who delivers it, who receives it, and who pays for it.
Author: Thomas H. Murray,Mark A. Rothstein,Robert F. Murray, Jr.
Publisher: Indiana University Press
The perfect resource for nursing students, as well as practicing nurses and physicians, this unique text explains the basics of the human genome: what it is, what it does, and its implications in health and disease.
Author: Edwin H. McConkey
Publisher: Jones & Bartlett Learning
Category: Health & Fitness
Describes potential uses for the ten-year, multimillion dollar Human Genome Project and its process of gene mapping; includes web citation for an interactive map of chromosomes.
Author: James Toriello
Publisher: The Rosen Publishing Group, Inc
Explores the ethical issues posed by genetic engineering.
The Human Genome Project and Theology
Author: Susan Brooks Thistlethwaite
Publisher: Fortress Press
An accessible discussion of what can be understood through human genome sequencing describes how the interactions of genes direct the growth of individuals, revealing what gene research will enable in the future. 20,000 first printing.
The History of the Human Genome
Author: Henry Gee
Publisher: W. W. Norton & Company
How do you explain flaw in a world engineered by God? Avise extends this age-old question to the most basic aspect of humanity's physical evidence-- our genes-- and provides the evolutionary answers.
A Case for Non-Intelligent Design
Author: John C. Avise
Publisher: Oxford University Press on Demand