Macleod's Clinical Diagnosis E-Book

Author: Alan G Japp,Colin Robertson

Publisher: Elsevier Health Sciences

ISBN: 0702051225

Category: Medical

Page: 368

View: 9317

Macleod’s Clinical Diagnosis is an innovative new book complementing its companion sister textbook, the internationally-respected Macleod’s Clinical Examination. It is a practical manual of clinical assessment that describes how common presenting problems are evaluated and diagnosed in modern clinical practice. This book will be an invaluable resource for senior medical students and junior doctors as they attempt to make the difficult transition from mastering basic clinical skills to assessing patients in the real world of clinical medicine. The format of the book is as follows: Part 1: The principles of clinical assessment: in addition to defining the scope and remit of the book this initial group of chapters invites readers to reconsider the overall aims of clinical assessment, the contribution that each element of the assessment can make to these aims and how the approach must be adapted to fit the clinical context. It also touches on diagnostic theory and explains some different approaches to diagnosis. Part 2: How to assess common presenting problems: this section forms the core of the book and consists of a series of ‘diagnostic guides’ covering the major presenting problems in medicine and surgery; these provide the reader with a system for how to use the tools of history-taking, physical examination and routine tests to arrive at a logical differential diagnosis. The guides also cover some limited ‘post-diagnosis information’ in the form of severity/prognostic indicators. A unique book allowing a reader to apply the skills of clinical examination in the formulation of a differential diagnosis and placing a patient’s symptoms in context. Takes a problem-based approach to diagnostic reasoning, reflecting both modern medical and current educational practices. Builds on the clinical skills outlined in the companion Macleod’s Clinical Examination textbook.
Posted in Medical

Macleod's Clinical OSCEs

Author: Paul A. O'Neill,Alexandra Evans,Tim Pattison,Meriel Tolhurst-Cleaver,Serena Tolhurst-Cleaver

Publisher: Elsevier Health Sciences

ISBN: 0702054828

Category: Medical

Page: 340

View: 9375

This new book for medical students contains over 60 of the most commonly encountered OSCE stations in medicine and surgery. The OSCEs are arranged according to type of skill; for example history-taking, ethics and communication, physical examination. This is an accessible book for students under pressure who are revising for a clinical OSCE. It provides simple advice, tips about preparation, and will be easily understood. It provides sample OSCE station questions and simulated patient scripts (with answers) for practice at home. Provides sample OSCE station questions and simulated patient scripts (with answers) for practice at home. Will give an insight into how to ‘Get inside the examiners head’ to help the student do better in the OSCE station. Highlights ‘red flag’ situations and explains the underlying importance of these topics. Includes advice both on how to excel and on common errors at each OSCE station. Several of the OSCE stations give details of how more advanced students would be expected to perform at higher levels. Includes online access to sample marking sheets.
Posted in Medical

Clinical Examination

A Systematic Guide to Physical Diagnosis

Author: Nicholas J. Talley,Simon O'Connor

Publisher: Elsevier Health Sciences

ISBN: 0729541479

Category: Medical

Page: 590

View: 3454

A bestselling title for over 25 years, the updated seventh edition of Talley and O'Connor's Clinical Examination is an essential read for all student clinicians. Fully updated with the latest clinical data, including specially commissioned research, this new edition of Clinical Examination addresses the core principles and clinical skills that underpin diagnosis for safe, effective medical practice. Clinical Examination: A systematic guide to physical diagnosis, 7th edition breaks down each body system into a logical framework focusing on the history, clinical examination and correlation between physical signs and disease for each system. Helping students navigate from first impressions though to the end of consultation, the text provides a patient-centric, evidence-based approach, making it the definitive resource for anyone embarking upon a medical career. Building on the strengths of previous editions, Clinical Examination 7th edition, also includes via Student Consult: - New OSCE based scenario videos featuring Nick Talley and Simon O'Connor to assist with examination preparation - ECG case studies - Imaging library (X-Rays, MRIs and CT Scans) Please note Student Consult access is only available with purchase of a print copy. Available from 28 March 2014 - for separate purchase to enrich your learning experience: An enhanced eBook version containing all content from the print edition plus 4 additional chapters covering history and examination of Gynaecology, Obstetrics, Neonatology and Paediatrics, new OSCE videos featuring Nick Talley and Simon O'Connor, ECG case studies, an imaging library and MCQs. Purchase can be made via Inkling from 28 March 2014 (www.inkling.com) Building on the strengths of previous editions, Clinical Examination 7th edition, also includes via Student Consult: - OSCE based scenario videos to assist with examination preparation - ECG case studies - Imaging library (X-Rays, MRIs and CT Scans) Please note Student Consult access is only available with purchase of a print copy. - Chapters have been extended into sections, with each section covering a body system, incuding chapters on history, clinical examination and correlatio of physical signs and disease. - Building on the strengths of previous editions, Clinical Examination 7th edition, also includes via Student Consult: - Brand new OSCE based scenario videos to assist with examination preparation - ECG case studies - Imaging library (X-Rays, MRIs and CT Scans) - Please note Student Consult access is only available with purchase of a print copy. - From 28 March 2014 an enhanced eBook will also be available containing all content from this edition plus 4 additional chapters covering history and examination of Gynaecology, Obstetrics, Neonatology and Paediatrics, OSCE videos, ECG case studies, an imaging library and MCQs. From 28 March 2014 purchase can be made via Inkling (www.inkling.com) The book is written for the clinical skills subject of the medical curriculum. Medical schools teach this at varying stages, some introducing the subject in the beginning years (graduate medical schools years 1 & 2) and others at year 3 (traditional/hybrid curricula, usually 5 or 6 years). Specialty Colleges and RACP teach a clinical skills subject in the early part of basic training which takes place after PGY1 & 2.
Posted in Medical

Introduction to Clinical Examination

Author: Michael J. Ford,Iain Hennessey,Alan Japp

Publisher: Elsevier Health Sciences

ISBN: 0443074178

Category: Medical

Page: 180

View: 6046

The most important core skills for medical students to master are history taking and clinical examination. This extensively revised, eighth edition has been written with the philosophy that the acquisition of clinical skills is most effectively undertaken at the bedside. This pocketbook should be used as a companion, to be taken onto the wards and into consulting rooms where the information is most needed. The book begins with a system of history taking followed by a new chapter on the analysis of key symptoms. The remaining chapters cover physical examination of each of the major systems. Each stage of the examination starts with a detailed, step-by-step description of the examination method complemented by relevant illustrations, diagrams and tables on the facing page. This book is intended primarily for use at the outset of clinical training; once students have achieved proficiency in the basic skills of interviewing and examining, the book should also prove useful for revision. An invaluable starter book concentrating purely on the fundamentals of performing a patient examination. Covers each body system and outlines the principles of: - taking a history - how to conduct a physical examination - specific examination points as appropriate Concentrates only on the main symptoms of disease and then the normal and abnormal physical findings. Mention of specific diseases is confined to those most commonly encountered. Compact and pocket-sized to be carried around easily. · Now in full colour double-page format · Clear simple colour line drawings covering the essentials of a clinical examination. · Published simultaneously with the Eleventh Edition of Macleod's Clinical Examination
Posted in Medical

Macleod's Clinical Examination E-Book

Author: J. Alastair Innes,Anna R Dover,Karen Fairhurst

Publisher: Elsevier Health Sciences

ISBN: 0702069914

Category: Medical

Page: 448

View: 6436

This classic textbook aims to assist clinicians develop the consultation skills required to elicit a clear history, and the practical skills needed to detect clinical signs of disease. Where possible, the physical basis of clinical signs is explained to aid understanding. Formulation of a differential diagnosis from the information gained is introduced, and the logical initial investigations are included for each system. The first part of the book addresses the general principles of good interaction with patients, from the basics of taking a history and examining, to the use of pattern recognition to identify spot diagnoses. The second part documents the relevant history, examination and investigations for all the major body systems. The third part illustrates the application of these skills to specific clinical situations. The final part covers preparation for assessments of clinical skills and the use of these skills in everyday practice. The book has accompanying videos demonstrating many of the key clinical examination routines as set out in the book. A new editorial team has undertaken a substantial review of the book’s contents and with the help of many new authors has radically revised the order and approach of the text. Several new chapters have been created including a chapter on patients with mental disorders; a chapter covering the approach to a deteriorating patient; a chapter on assessment of patients towards the end of life and two new chapters on applying the key clinical skills during assessments and in practice. The structure of the text has been rationalised with careful use of boxes, tables and figures to set out the concepts for maximum clarity.
Posted in Medical

250 Cases in Clinical Medicine E-Book

Author: Ragavendra R. Baliga

Publisher: Elsevier Health Sciences

ISBN: 0702050261

Category: Medical

Page: 928

View: 337

A new, fully updated edition of Baliga's very popular collection of short cases arranged by clinical area, emphasising the key diagnostic features of clinical conditions as commonly presented in the short-case part of the Final MB and MRCP examinations. Also included are likely instructions or commands expected from the examiner for each condition, and the key points which the candidate must tell the examiner. A must-have for the final-year undergraduate and trainee doctor. From customer reviews of the previous edition: 'This book is the most useful guide that money can buy for the final exams in the current MBChB undergraduate course. It covers important areas of clinical medicine in a question based format and highlights classical scenarios. The questions raised are classical of examiners in the long and short case examinations. This is a must buy for any undergraduate medical student!!!' 'The book is a must during the period that the young doctor or student is on the wards. It allows one to focus on the important physical findings and the relavant clinical pearls associated with the different medical conditions met... It discusses important physical findings and their diagnostic importance. I have found it useful in preparing for attending ward rounds and also for sharpening my clinical skills. The discussion section is well organised such that undergraduates as well as postgraduates can benefit and the material is up to date with good references for further reading.' 'Excellent preparation for finals as well the MRCP ...MUST HAVE before MRCP PACES.' Features Ideal for use in the ward. Each of the 250 cases presents a disease or topic which is covered consistently to address:● salient features ● history ● examination ● diagnosis ● questions covering investigations and differentiations ● advanced-level questions ● management. New to this edition: Over 350 new images Enhanced advanced-level questions Many more tables
Posted in Medical

Davidson's Self-assessment in Medicine E-Book

Author: Deborah Wake,Patricia Cantley

Publisher: Elsevier Health Sciences

ISBN: 070207148X

Category: Medical

Page: 416

View: 6090

Davidson’s Assessment in Medicine is a collection of 1250 best-of-five multiple choice questions, arranged to correspond with the chapters of the Twenty-third Edition of Davidson's Principles and Practice. The questions follow the style used in many international undergraduate and early postgraduate exams. For each question the answers are accompanied by a short piece of remediation/ feedback with references back to the main textbook for further information. This book is an excellent broad assessment text and forms a highly useful complement to the main textbook. It will help students increase the efficiency with which they acquire the factual knowledge necessary for both passing examinations and good medical practice. Although written to accompany Davidson's Principles and Practice of Medicine, this book can be used alongside any clinical medicine textbook. 1250 best-of-five multiple choice questions with detailed answers and remediation feedback. Closely linked to the world-renowned Davidson's Principles and Practice of Medicine textbook.
Posted in Medical

API Textbook of Medicine, Ninth Edition, Two Volume Set

Author: Y P Munjal,Surendra K Sharm

Publisher: JP Medical Ltd

ISBN: 9350250748

Category: Medical

Page: 2228

View: 3683

The API (Association of Physicians of India) Textbook of Medicine consists of 28 sections across two comprehensive volumes covering a wide range of medical disorders. Fully revised and with 1588 images, illustrations and tables, this new edition has many new chapters on topics including nanotechnology and nano-medicine, and clinical approach to key manifestations. Each section is dedicated to a different medical phenomenon, including clinical pharmacology, endocrinology, dermatology, infectious diseases and nutrition. Also included is online access to teaching modules for teachers and students, questions and answers, an atlas/image bank, echocardiography and video EEG and common medical procedures with voice over.
Posted in Medical

Mosby's Review Questions for the Speech-Language Pathology PRAXIS Examination E-Book

Author: Dennis M. Ruscello,Mosby

Publisher: Elsevier Health Sciences

ISBN: 0323081207

Category: Medical

Page: 376

View: 7207

With approximately 1,400 practice questions – more than any other exam review – this book provides the most complete, reliable preparation available for the PRAXIS II subject assessment examination. Review questions can be selected to match the style and question distribution of the real exam to familiarize you with the examination experience and help you build test-taking confidence. This title includes additional digital media when purchased in print format. For this digital book edition, media content is not included.
Posted in Medical

Paediatrics

Author: Rajat Kapoor,Katy Barnes

Publisher: Mosby

ISBN: 9780723436355

Category: Medical

Page: 313

View: 6406

Crash Course - your effective every day study companion PLUS the perfect antidote for exam stress! Save time and be assured you have all the information you need in one place to excel on your course and achieve exam success. A winning formula now for over 15 years, each series volume has been fine tuned and fully updated, with an improved layout tailored to make your life easier. Especially written by junior doctors - those who understand what is essential for exam success - with all information thoroughly checked and quality assured by expert Faculty Advisers, the result is a series of books which exactly meets your needs and you know you can trust. Building on the success of previous editions, Crash Course Paediatrics 4/e provides concise and highly practical overage of this core specialty. It has been carefully honed to meet the needs of students in their medical undergraduate years, but will also prove invaluable for foundation trainees or specialty doctors embarking on a career in paediatrics. More than 400 tables and illustrations present clinical, diagnostic and practical information in an easy-to-follow manner Friendly and accessible approach to the subject makes learning especially easy Written by junior doctors for students - authors who understand exam pressures Contains 'Hints and Tips' boxes, and other useful aide-mémoires Succinct coverage of the subject enables 'sharp focus' and efficient use of time during exam preparation Contains a fully updated self-assessment section - ideal for honing exam skills and self-testing Self-assessment section fully updated to reflect current exam requirements Contains 'common exam pitfalls' as advised by faculty Feeling daunted? Worried about passing your exams? Need to brush up on a particular topic? Then Crash Course is for you!! Now celebrating over 10 years of success - Crash Course has been specially devised to help you get through your exams with ease. Completely revised and updated throughout, the new edition of Crash Course is perfectly tailored to meet your needs by providing everything you need to know in one place. Clearly presented in a tried and trusted, easy-to-use, format, each book in the series gives complete coverage of the subject in a no-nonsense, user-friendly fashion. Commencing with 'Learning Objectives', each chapter guides you succinctly through the topic, giving full coverage of the curriculum whilst avoiding unnecessary and often confusing detail. Each chapter is also supported by a full artwork programme, and features the ever popular 'Hints and Tips' boxes as well as other useful aide-mémoires. All volumes contain an up-to-date self-assessment section which allows you to test your knowledge and hone your exam skills! Authored by students or junior doctors - working under close faculty supervision - each volume has been prepared by someone who has been in the exam situation and so can relate closely to your needs. So whether you need to get out of a fix or aim for distinctionCrash Course is for you!! Be safe - rely on Crash Course!
Posted in Medical

40 Days of Dating

An Experiment

Author: Timothy Goodman,Jessica Walsh

Publisher: ABRAMS

ISBN: 1613127154

Category: Self-Help

Page: 304

View: 5378

“What would happen if Harry met Sally in the age of Tinder and Snapchat? . . . A field guide to Millennial dating in New York City” (New York Daily News). When New York–based graphic designers and long-time friends Timothy Goodman and Jessica Walsh found themselves single at the same time, they decided to try an experiment. The old adage says that it takes 40 days to change a habit—could the same be said for love? So they agreed to date each other for 40 days, record their experiences in questionnaires, photographs, videos, texts, and artworks, and post the material on a website they would create for this purpose. What began as a small experiment between two friends became an Internet sensation, drawing 5 million unique (and obsessed) visitors from around the globe to their site and their story. 40 Days of Dating: An Experiment is a beautifully designed, expanded look at the experiment and the results, including a great deal of material that never made it onto the site, such as who they were as friends and individuals before the 40 days and who they have become since.
Posted in Self-Help

Clinical Medicine

A Textbook for Medical Students and Doctors

Author: Parveen June Kumar,Michael L. Clark

Publisher: Bailliere Tindall Limited

ISBN: 9780702020193

Category: Clinical medicine

Page: 1326

View: 8507

This is much more than an introduction to medicine but with just enough detail not to overwhelm. Clinical Medicine effectively communicates the latest developments in many fast-changing areas.
Posted in Clinical medicine

Developmental Phonological Disorders

Foundations of Clinical Practice, Second Edition

Author: Susan Rvachew,Françoise Brosseau-Lapré

Publisher: Plural Publishing

ISBN: 1944883703

Category: Medical

Page: 624

View: 1704

Developmental Phonological Disorders: Foundations of Clinical Practice, Second Edition is the only graduate-level textbook designed for a competency-based approach to teaching, learning, and assessment. The book provides a deep review of the knowledge base necessary for the competent assessment, diagnosis, and treatment of developmental phonological disorders. Thoroughly revised and updated, the textbook contains learning objectives in each chapter to further support understanding of concepts and carefully designed case studies and demonstrations to promote application to clinical problem solving. Key Features: Learning objectives for each chapter subsectionIncludes the "how, why, and when" to apply each assessment and treatment procedure in clinical practice62 tables containing clinically relevant information such as normative data to interpret phonological assessment results99 figures to support clinical decision making such as recommending a treatment delivery model, selecting treatment targets, or choosing evidence-based interventions35 case studies to support a competency-based approach to teaching and assessment35 demonstrations that show how to implement assessment and treatment procedures The second edition provides a comprehensive overview of seminal studies and leading-edge research on both phonological development and phonological disorders, including motor speech disorders and emergent literacy. This wealth of theoretical background is integrated with detailed descriptions and demonstrations of clinical practice, allowing the speech-language pathologist to design interventions that are adapted to the unique needs of each child while being consistent with the best research evidence. New to the Second Edition: Updated and expanded section on childhood apraxia of speechUpdated and expanded sections on the identification and treatment of inconsistent phonological disorderAdministration and interpretation of the Syllable Repetition Task addedAdministration and interpretation of the Diagnostic Evaluation of Articulation and Phonology added with case studies and demonstrationsNew organization, formatting, and editing to reduce the size of the bookCase studies revised to a single-page formatImproved Table of Contents to ease access to content, including norms tables, case studies, and demonstrations
Posted in Medical

Essentials of Kumar and Clark's Clinical Medicine E-Book

Author: Anne Ballinger

Publisher: Elsevier Health Sciences

ISBN: 0702050148

Category: Medical

Page: 992

View: 705

Mini Kumar & Clark goes into its fifth edition! New to this best-selling, portable, quick reference to clinical medicine: Fully updated in line with the latest edition of Kumar & Clark’s Clinical Medicine New chapter on malignant disease Practical procedures and therapeutics taken into individual chapters as appropriate. From reviews of the previous edition: ‘This really is an excellent medical textbook ... Easily covers undergraduate medicine.’ ‘Pocket Essentials is a great little book to review the night before you start on a rotation. It is small enough that you can easily read over the chapter and then appear on the ward with a good idea of what is going on.’ ‘In short this book is concise, succinct and gets straight to the point.’ ‘This book summarises everything you need to know: causes, diagnoses and treatments.’ ‘I am finding this book very helpful and more importantly very concise. It has most things you need to know about common clinical pathologies.’ ‘... I turned to Pocket Essentials of Clinical Medicine as my clinical medicine reference guide – and what a guide! An excellent book, which gives you the clinical features, investigations and management for a whole variety of different illnesses. The book is clearly laid out, and even has normal blood chemistry values at the end. Do yourself a favour and buy this book!’ ‘This mini paperback is a must for anyone studying medicine. It gives all the information one would need and all without the pain of carrying around a large book.’ ‘I liked this book ... it was useful having a smaller reference book ... to carry around on wards etc. – it's more digestible and easier to follow than big K&C, and gives a little more background than the Oxford Handbook – and I know people who use it to revise for finals.’
Posted in Medical

Peripheral Neuropathies in Clinical Practice

Author: Steven Herskovitz,Stephen Scelsa,Herbert Schaumburg

Publisher: OUP USA

ISBN: 0195183266

Category: Medical

Page: 382

View: 6340

"Peripheral Neuropathies in Clinical Practice is a revamped and updated version of Disorders of Peripheral Nerves, published in 1992. The current edition begins with basic concepts and anatomic classifications of the Peripheral Nervous System (PNS) and its disorders." "The anatomic complexities, varied presentations, and innumerable etiologies of peripheral neuropathies present substantial challenges for the practicing clinician. Comprehensive and concise in approach, Peripheral Neuropathies in Clinical Practice is a thorough review of the neurologic literature written by expert clinicians, each of whom are leaders in the field. Its aim is to assist neurologists, trainees in neurology and related fields, and all practitioners who see these patients to better understand, evaluate, and manage peripheral nerve disorders."--BOOK JACKET.
Posted in Medical

Genetic Neuromuscular Disorders

A Case-Based Approach

Author: Corrado Angelini

Publisher: Springer

ISBN: 3319075004

Category: Medical

Page: 384

View: 1555

This book describes the genetic diagnostic entities of neuromuscular disorders. Each neuromuscular syndrome is presented clinically as a case study, accompanied by text reviewing different molecular defects, DNA research and differential diagnosis. This collection of neuromuscular disorders features the different clinical phenotypes related to each genotype and are representative of the whole spectrum of a genetic muscle disorder, helping the clinician and neuromuscular physician to make a diagnosis. Key points for each genetic disease are identified to suggest treatment, when available, or the main clinical exams useful in follow-up of patients. Genetic Neuromuscular Disorders: A Case-Based Approach is aimed at neuromuscular physicians and neurology residents.
Posted in Medical

100 Cases in Clinical Medicine, Third Edition

Author: P John Rees,James Pattison,Christopher Kosky

Publisher: CRC Press

ISBN: 1444174290

Category: Medical

Page: 275

View: 1370

Making speedy and appropriate clinical decisions and then choosing the best course of action is an essential skill for doctors. Exploring initial medical assessment, 100 Cases in Clinical Medicine presents 100 scenarios commonly seen by medical students and junior doctors in the emergency or outpatient department, on the ward, or in the community setting. Each case begins with a succinct summary of the patient's history, examination, and initial investigation. The text includes photographs where relevant and questions on the diagnosis and management of each case. The answers provide a detailed discussion on each topic, with further illustration where appropriate. Most of the cases included are common problems but the book also includes more unusual cases to illustrate specific points and to emphasize that rare things do present. The first 20 cases are arranged by systems; the next 80 are in random order because symptoms such as breathlessness and pain may relate to many different clinical problems in various systems. These true-to-life cases will teach students and junior doctors to recognize important clinical symptoms and signs and to develop the diagnostic and management skills needed for the cases they will encounter on the job.
Posted in Medical

Essential Evidence-Based Medicine

Author: Dan Mayer

Publisher: Cambridge University Press

ISBN: 9780521540278

Category: Medical

Page: 381

View: 2526

Although using the results of the best research to determine the best care for an individual patient may appear very simple, most medical students and physicians do not have the mathematical background or training to critically evaluate published research. This "user's guide" helps the medical professional to become a more discriminating reader of medical literature, and ultimately better equipped to apply evidence-based medicine in practice. The volume will be an ideal introductory text for medical students and health-care professionals.
Posted in Medical

Adult ADHD

Diagnostic Assessment and Treatment

Author: J.J. Sandra Kooij

Publisher: Springer Science & Business Media

ISBN: 1447141385

Category: Medical

Page: 294

View: 3688

Adult ADHD: Diagnostic Assessment and Treatment, Third Edition covers not only diagnostic assessment, but also comorbidity patterns as well as differential diagnosis of ADHD with for example bipolar disorder and borderline personality disorder. The symptom overlap and misdiagnosis of chronic fatigue syndrome in girls and women with the inattentive subtype of ADHD, ADD is explored. The chronic delayed sleep phase syndrome associated with ADHD based on disturbances in the circadian rhythm, and the possible consequences for general health (obesity, diabetes, cardiovascular diseases and cancer) are discussed. There are sections on ADHD and intelligence, criminality, sexuality, dyslexia and autism. Adult ADHD can be treated effectively but as yet the disorder is not always recognised by professionals and this book aims to help correct this. Diagnostic tools are included, such as the structured Diagnostic Interview for Adult ADHD (DIVA), and an ultra-short and somewhat longer screening tool, all based on the DSM-IV criteria for ADHD. Treatment options cover psychoeducation and motivation and individual and group coaching; long-acting stimulants and other new drugs for treating ADHD; use of melatonin to treat the delayed sleep-phase disorder. Useful information is included on the setting up and organisation of a department for adult ADHD with a multidisciplinary team. References, websites and useful international addresses have all been updated. Adult ADHD: Diagnostic Assessment and Treatment, Third Edition is intended for students, junior doctors/residents, psychologists, psychiatrists, other mental healthcare professionals and interested parties and provides a quick overview of the current state of the science and of the methods used in diagnosis and treatment. Adult ADHD: Diagnostic Assessment and Treatment, Third Edition was originally published by Pearson Assessment and Information BV, The Netherlands.
Posted in Medical

Hereditary Colorectal Cancer

Proceedings of the Fourth International Symposium on Colorectal Cancer (ISCC-4) November 9–11, 1989, Kobe Japan

Author: Joji Utsunomiya,Henry T. Lynch

Publisher: Springer Science & Business Media

ISBN: 4431683372

Category: Medical

Page: 575

View: 870

Since the success in chemical induction of cancer in rabbit's ear skin by K. Yamagiwa in 1915, oncologists of the world have come to believe that they can only solve their problems by means of animal experimen tation. The importance of environmental factors became moreevident in 1935 when T. Yoshida and T. Sasaki introduced azodye hepatocarcino genesis in rats. In the domain of the gastrointestinal tract, T. Sugimura has more recently accumulated enough evidence to indicate that locally active chemical mutagens are carcinogenic. In contrast, principal approaches to colorectal tumors have been quite different: emphasis has been placed on gene identification. Long before cancer of the large bowel was recognized, importance of the roles of adenomatosis coli and its familial occurrence attracted the attention of epidemiologists and geneticists. Morphological characteri zation and analysis of hereditary trends of human material have already bad a long history, and recently detailed analysis of genetic material has become feasible in the wake of rapid development in our knowledge of the oncoviruses, oncogenes, suppressor genes, chromosomal and DNA mapping, molecular mutation and so on. lt is true that in colorectal pathology, and in no other field, these areas of research have been explored more extensively and decisively. The identification of previ ously ill-defined lesions such as precancers and benign neoplasms have been improved because sequential changes can be observed in multiple samples spread over a wide area and followed up in due course.
Posted in Medical