Introduction to Pharmaceutical Chemical Analysis

Author: Steen Honor? Hansen,Stig Pedersen-Bjergaard,Knut Rasmussen

Publisher: John Wiley & Sons

ISBN: 0470661216

Category: Medical

Page: 494

View: 8686

This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the pharmacy student, to teach the requirements in “analytical chemistry” for the 5 years pharmacy curriculum, but the textbook is also intended for analytical chemists moving into the field of pharmaceutical analysis. Addresses the basic concepts, then establishes the foundations for the common analytical methods that are currently used in the quantitative and qualitative chemical analysis of pharmaceutical drugs Provides an understanding of common analytical techniques used in all areas of pharmaceutical development Suitable for a foundation course in chemical and pharmaceutical sciences Aimed at undergraduate students of degrees in Pharmaceutical Science/Chemistry Analytical Science/Chemistry, Forensic analysis Includes many illustrative examples
Posted in Medical

Practical Pharmaceutical Chemistry

Part II Fourth Edition

Author: A. H. Beckett,J. B. Stenlake

Publisher: A&C Black

ISBN: 9780485113235

Category: Science

Page: 320

View: 7560

This Fourth Edition has been thoroughly revised and updated to take account of international developments in pharaceutical chemistry and to maintain the position of Practical Pharmaceutical Chemistry as the leading University textbook in the field of pharaceutical analysis and quality control. Part 2 deals with physical techniques of analysis for more advanced courses. It gives a broad coverage of the most widely used techniques in quantative chromatography. The treatmentof spectroscopy and radiopharmaceuticals has also been increased. Thre are additional chapters on the contribution and role of physical methods of analysis in the various stages of drug development; and a series of workshop-style exercises, illustrating the application of spectroscopic techniques in structural elucidation and verification of identity. Users of the two volumes will welcome the internationalisation of the text, with examples based on drugs and dosage forms that are widespread and in commun use in human medicine in Britain, continental Europe and North America. Additionally there is some reference to veterinary pharmaceuticals where they provide appropriate examples.
Posted in Science

Instrumentelle Analytik

Grundlagen - Geräte - Anwendungen

Author: Douglas A. Skoog,F. James Holler,Stanley R. Crouch

Publisher: Springer Spektrum

ISBN: 9783642381690

Category: Science

Page: 1030

View: 2944

Das Standard-Lehrbuchs zur Instrumentellen Analytik, begründet von Skoog und Leary, ist hiermit endlich wieder auf Deutsch verfügbar. Als stark erweiterte, komplett überarbeitete Ausgabe unterstützt es fortgeschrittene Studenten der Chemie an Universitäten und Hochschulen. Es berücksichtig die Anforderungen einer großen Vielfalt an Disziplinen, die ein Grundwissen in Analytischer Chemie benötigen, und richtet sich damit auch an Physiker, Ingenieure und Biochemiker. Das Buch führt aktuell und kompetent in die Grundzüge und Feinheiten der heutigen Instrumentellen Analytischen Chemie ein. Der Focus liegt in diesem Buch auf den theoretischen Grundlagen der diversen Gerätetypen, deren optimales Anwendungsgebiet, Empfindlichkeit und Präzision sowie deren Grenzen. Über 700 detailreiche, selbsterklärende Abbildungen, Anhänge zu Statistik und Elektronik, Übungsaufgaben mit Lösungen und viele wichtige Originalzitate ergänzen dieses moderne Lehrbuch für Studierende und Praktiker.
Posted in Science

Geschichte der analytischen Chemie

Author: Ferenc Szabadváry

Publisher: N.A

ISBN: N.A

Category: Chemistry, Analytic

Page: 410

View: 3943

Posted in Chemistry, Analytic

Essentials of Pharmaceutical Chemistry

Author: Donald Cairns

Publisher: Pharmaceutical Press

ISBN: 0853699798

Category: Medical

Page: 308

View: 6124

An introduction to pharmaceutical chemistry for undergraduate pharmacy, chemistry and medicinal chemistry students. Essentials of Pharmaceutical Chemistry is a chemistry introduction that covers all of the core material necessary to provide an understanding of the basic chemistry of drug molecules. Now a core text on many university courses, it contains numerous worked examples and problems. The 4th edition includes new chapters on Chromatographic Methods of Analysis, and Medicinal Chemistry - The Science of Drug Design.
Posted in Medical

Karl-Fischer-Titration

Methoden zur Wasserbestimmung

Author: Eugen Scholz

Publisher: Springer-Verlag

ISBN: 3642693687

Category: Science

Page: 138

View: 1540

Posted in Science

Pharmaceutical Chemistry

Author: Jill Barber,Chris Rostron

Publisher: Oxford University Press

ISBN: 0199655308

Category: Medical

Page: 368

View: 589

Taking medication is a common occurrence for many people, whether it is to soothe an aching head, regulate blood sugars, or treat life-threatening conditions such as HIV or cancer. Examining how drugs are manufactured, formulated, and the way that they work in our bodies, Pharmaceutical Chemistry provides a wide-ranging overview of organic chemistry as it is applied to the study and practice of pharmacy. FEATURES * Supports an integrated pharmacy education * Focuses on the fundamental ideas that first-year students need to fully grasp before progressing in their studies * Demonstrates the connections between scientific concepts and principles and how they are applied to pharmacy * Written and edited by experts who have a wealth of teaching experience COMPANION WEBSITE For registered adopters of the book: - Figures from the book, available to download For students: - Self-assessment questions for each chapter - Related additional resources ABOUT THE SERIES The Integrated Foundations of Pharmacy series supports those who are at the beginning of their journey to become a pharmacist. Students will begin to understand how a drug molecule is made; the process that turns it into a medicine; the role the pharmacist has when dispensing that medicine; and what happens in the body when it is taken. Most importantly, the series shows how each of these aspects are integrated, reflecting the most up-to-date teaching practices.
Posted in Medical

Untersuchungen über die radioaktiven Substanzen

Author: Marie Curie

Publisher: BoD – Books on Demand

ISBN: 3845722223

Category: Science

Page: 144

View: 5170

Marie Sklodowska Curie, Trägerin des Nobelpreises für Physik und für Chemie, untersuchte die von Henri Becquerel beobachtete Strahlung von Uranverbindungen. Gemeinsam mit ihrem Mann Pierre entdeckte sie das Radium und das Polonium und prägte den Begriff „radioaktiv“. Ihre Forschungsergebnisse fasste sie in ihrer hier vorliegenden Dissertation zusammen, die innerhalb eines Jahres in fünf Sprachen übersetzt wurde. Sorgfältig bearbeiteter Nachdruck der deutschsprachigen Ausgabe aus dem Jahr 1904.
Posted in Science

Global New Drug Development

An Introduction

Author: Jan A. Rosier,Mark A. Martens,Josse R. Thomas

Publisher: John Wiley & Sons

ISBN: 1118414853

Category: Medical

Page: 424

View: 2091

The development of new drugs is very complex, costly and risky. Its success is highly dependent on an intense collaboration and interaction between many departments within the drug development organization, external investigators and service providers, in constant dialogue with regulatory authorities, payers, academic experts, clinicians and patient organizations. Within the different phases of the drug life cycle, drug development is by far the most crucial part for the initial and continued success of a drug on the market. This book offers an introduction to the field of drug development with a clear overview of the different processes that lead to a successful new medicine and of the regulatory pathways that are used to launch a new drug that are both safe and efficacious. "This is the most comprehensive and detailed book on drug development I have ever read and I feel that it is likely to become a staple of drug development courses, such as those taught at Masters Level in my own University.... I think in the light of increasing integration of company and academic approaches to drug development both sides can read this book... (and, therefore)... this book could not be more timely." —Professor Mike Coleman, University of Aston, UK ( from his review of the final manuscript)
Posted in Medical

Ionenaustauscher

Eigenschaften und Anwendungen

Author: Konrad Dorfner

Publisher: Walter de Gruyter

ISBN: 3111645681

Category: Reference

Page: 171

View: 1844

Posted in Reference

Bekenntnisse eines englischen Opiumessers

Author: Thomas De Quincey

Publisher: BoD – Books on Demand

ISBN: 3743707446

Category: Fiction

Page: 84

View: 4306

Thomas De Quincey: Bekenntnisse eines englischen Opiumessers Confessions of an English Opium-Eater. Erstdruck: 1821 in zwei Teilen im »London Magazine«, 1822 in Buchform. Hier in der Übersetzung von Leopold Heinemann, Berlin, Weltgeist-Bücher Verl.-Ges., 1927. Neuausgabe. Herausgegeben von Karl-Maria Guth. Berlin 2017. Umschlaggestaltung von Thomas Schultz-Overhage unter Verwendung des Bildes: Sir John Watson-Gordon, Porträt des Thomas De Quincey, undatiert.. Gesetzt aus der Minion Pro, 11 pt.
Posted in Fiction

An Introduction to Medicinal Chemistry

Author: Graham Patrick

Publisher: Oxford University Press

ISBN: 0198749694

Category: Pharmaceutical chemistry

Page: 832

View: 2175

For many people, taking some form of medication is part of everyday life, whether for mild or severe illness, acute or chronic disease, to target infection or to relieve pain. However for most it remains a mystery as to what happens once the drug has been taken into the body: how do the drugs actually work? Furthermore, by what processes are new drugs discovered and brought to market?An Introduction to Medicinal Chemistry, sixthedition, provides an accessible and comprehensive account of this fascinating multidisciplinary field. Assuming little prior knowledge, the text is ideal for those studying the subject for the first time. Inaddition to covering the key principles of drug design and drug action, the text also discusses important current topics in medicinal chemistry. The subject is brought to life throughout by engaging case studies highlighting particular classes of drugs, and the stories behind their discovery and development.
Posted in Pharmaceutical chemistry

Spektroskopische Methoden in der organischen Chemie

Author: Manfred Hesse,Herbert Meier,Bernd Zeeh

Publisher: Georg Thieme Verlag

ISBN: 9783135761077

Category: Organic compounds

Page: 456

View: 3605

Posted in Organic compounds

Introduction to Chemical Engineering Analysis Using Mathematica

Author: Henry C. Foley

Publisher: Elsevier

ISBN: 0080534953

Category: Technology & Engineering

Page: 507

View: 2322

This book provides an introduction to chemical engineering analysis- which reviews the processes and designs used to manufacture, use, and dispose of chemical products-and to Mathematica, one of the most powerful mathematical software tools available for symbolic, numerical, and graphical computing. Analysis and computation are explained simultaneously. The book covers the core concepts of chemical engineering, ranging from the conservation of mass to chemical kinetics. At the same time the text shows how to use the latest version of Mathematica, from the basics of writing a few lines of code through developing entire analysis programs.
Posted in Technology & Engineering

High Performance Liquid Chromatography

Fundamental Principles and Practice

Author: W.J. Lough,I.W. Wainer

Publisher: CRC Press

ISBN: 9780751400762

Category: Science

Page: 288

View: 9119

High performance liquid chromatography (HPLC) has long been recognized as one of the most useful and versatile analytical techniques. It has now progressed from being a highly expensive method of analysis to a routine technique with wide applications. Consequently there is a requirement in many chemistry and chemistry-related courses for students to acquire a detailed understanding of the principles and practice of HPLC. Written in a manner suitable for undergraduate students studying analytical chemistry and learning about chromatographic analytical techniques applied to pharmaceutical analysis, biochemistry and related disciplines, High-performance Liquid Chromatography: Fundamental Principles and Practice introduces the fundamentals of HPLC. Loosely structured in three parts, the text begins with a thorough introduction of the subject and then progresses through the essential knowledge of the instrumentation needed for HPLC. The final part covers with the applications of HPLC in real-world situations. Developed by a team of international experts from a wide cross-section of disciplines, the text is relevant to a wide range of courses.
Posted in Science

NMR Spectroscopy in Pharmaceutical Analysis

Author: Iwona Wawer,Bernd Diehl

Publisher: Elsevier

ISBN: 008095152X

Category: Science

Page: 528

View: 7964

For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples. Combines theory, techniques, and concrete applications—all of which closely resemble the laboratory experience Considers international pharmacopoeias, addressing the concern for licensing Features the work of academics and researchers, appealing to a broad readership
Posted in Science

Statistical Methods in Analytical Chemistry

Author: Peter C. Meier,Richard E. Zünd

Publisher: John Wiley & Sons

ISBN: 0471726117

Category: Science

Page: 456

View: 5289

This new edition of a successful, bestselling book continues toprovide you with practical information on the use of statisticalmethods for solving real-world problems in complex industrialenvironments. Complete with examples from the chemical andpharmaceutical laboratory and manufacturing areas, this thoroughlyupdated book clearly demonstrates how to obtain reliable results bychoosing the most appropriate experimental design and dataevaluation methods. Unlike other books on the subject, Statistical Methods inAnalytical Chemistry, Second Edition presents and solves problemsin the context of a comprehensive decision-making process under GMPrules: Would you recommend the destruction of a $100,000 batch ofproduct if one of four repeat determinations barely fails thespecification limit? How would you prevent this from happening inthe first place? Are you sure the calculator you are using istelling the truth? To help you control these situations, the newedition: * Covers univariate, bivariate, and multivariate data * Features case studies from the pharmaceutical and chemicalindustries demonstrating typical problems analysts encounter andthe techniques used to solve them * Offers information on ancillary techniques, including a shortintroduction to optimization, exploratory data analysis, smoothingand computer simulation, and recapitulation of errorpropagation * Boasts numerous Excel files and compiled Visual Basic programs-nostatistical table lookups required! * Uses Monte Carlo simulation to illustrate the variabilityinherent in statistically indistinguishable data sets Statistical Methods in Analytical Chemistry, Second Edition is anexcellent, one-of-a-kind resource for laboratory scientists andengineers and project managers who need to assess data reliability;QC staff, regulators, and customers who want to frame realisticrequirements and specifications; as well as educators looking forreal-life experiments and advanced students in chemistry andpharmaceutical science. From the reviews of Statistical Methods in Analytical Chemistry,First Edition: "This book is extremely valuable. The authors supply many veryuseful programs along with their source code. Thus, the user cancheck the authenticity of the result and gain a greaterunderstanding of the algorithm from the code. It should be on thebookshelf of every analytical chemist."-Applied Spectroscopy "The authors have compiled an interesting collection of data toillustrate the application of statistical methods . . . includingcalibrating, setting detection limits, analyzing ANOVA data,analyzing stability data, and determining the influence of errorpropagation."-Clinical Chemistry "The examples are taken from a chemical/pharmaceutical environment,but serve as convenient vehicles for the discussion of when to usewhich test, and how to make sense out of the results. Whilepractical use of statistics is the major concern, it is put intoperspective, and the reader is urged to use plausibilitychecks."-Journal of Chemical Education "The discussion of univariate statistical tests is one of the morethorough I have seen in this type of book . . . The treatment oflinear regression is also thorough, and a complete set of equationsfor uncertainty in the results is presented . . . The bibliographyis extensive and will serve as a valuable resource for thoseseeking more information on virtually any topic covered in thebook."-Journal of American Chemical Society "This book treats the application of statistics to analyticalchemistry in a very practical manner. [It] integrates PC computingpower, testing programs, and analytical know-how in the context ofgood manufacturing practice/good laboratory practice (GMP/GLP) . ..The book is of value in many fields of analytical chemistry andshould be available in all relevant libraries."-Chemometrics andIntelligent Laboratory Systems
Posted in Science